SK-MEL-1细胞系

SK-MEL-1/SK-MEL-1细胞系/SK-MEL-1细胞株/SK-MEL-1人皮肤黑色素瘤细胞

Cell line name SK-MEL-1

Synonyms SK-Mel-1; SK Mel 1; SK-Mel 1; SK-Mel1; SKMEL-1; SkMEL-1; SKMEL1; SK 1

Accession CVCL_0068

Resource Identification Initiative To cite this cell line use: SK-MEL-1 (RRID:CVCL_0068)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: MD Anderson Cell Lines Project.

From: Memorial Sloan Kettering Cancer Center; New York; USA.

Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK2004-052.

Population: Caucasian.

Doubling time: ~100 hours (DSMZ=ACC-303).

Microsatellite instability: Stable (MSS) (Sanger).

Omics: Deep exome analysis.

Omics: Deep phosphoproteome analysis.

Omics: Deep proteome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: Metastatic; Thoracic lymph duct; UBERON=UBERON_0007644.

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Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.

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A comprehensive transcriptional portrait of human cancer cell lines.

Nat. Biotechnol. 33:306-312(2015)

 

PubMed=25877200; DOI=10.1038/nature14397

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PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878

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TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Genome Med. 7:118.1-118.7(2015)

 

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469

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A landscape of pharmacogenomic interactions in cancer.

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PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076

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Characterization of human cancer cell lines by reverse-phase protein arrays.

Cancer Cell 31:225-239(2017)

 

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Screening human cell lines for viral infections applying RNA-Seq data analysis.

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Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Cancer Res. 79:1263-1273(2019)

 

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103

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Next-generation characterization of the Cancer Cell Line Encyclopedia.

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