CTLL-2细胞系

CTLL-2/CTLL-2细胞系/CTLL-2细胞株/CTLL-2小鼠T淋巴细胞

Cell line name CTLL-2

Synonyms CTLL 2; CTLL2; CTLL(2)

Accession CVCL_0227

Resource Identification Initiative To cite this cell line use: CTLL-2 (RRID:CVCL_0227)

Comments Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).

Characteristics: IL2 dependent.

Doubling time: 24 hours (PubMed=145543).

Cell type: T-cell; CL=CL_0000084.

Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)

Breed/subspecies: C57BL/6.

Hierarchy Children:

CVCL_KS71 (CellSensor irf1-bla CTLL-2) CVCL_6829 (CT.EV) CVCL_D100 (CTL44)

CVCL_YU23 (CTLL-2 NF-kappaB) CVCL_9786 (CTLL-20)

Category Transformed cell line

STR profile Source(s): PubMed=31220119

 

Markers:

Mouse STR 1-1 17

Mouse STR 1-2 19,20

Mouse STR 2-1 15,16

Mouse STR 3-2 14

Mouse STR 4-2 20.3

Mouse STR 5-5 17,18

Mouse STR 6-4 18,19

Mouse STR 6-7 17,20

Mouse STR 7-1 26.2

Mouse STR 8-1 16

Mouse STR 11-2 16

Mouse STR 12-1 17

Mouse STR 13-1 16

Mouse STR 15-3 22.3,23.3

Mouse STR 17-2 14,15

Mouse STR 18-3 16

Mouse STR 19-2 13,14

Mouse STR X-1 28,29

 

Run an STR similarity search on this cell line

Publications

PubMed=145543; DOI=10.1038/268154a0

Gillis S., Smith K.A.

Long term culture of tumour-specific cytotoxic T cells.

Nature 268:154-156(1977)

 

PubMed=9619491; DOI=10.1046/j.1440-1711.1998.00733.x

Weston L., Geczy A., Farrell C.

A convenient and reliable IL-2 bioassay using frozen CTLL-2 to improve the detection of helper T lymphocyte precursors.

Immunol. Cell Biol. 76:190-192(1998)

 

PubMed=9744750; DOI=10.1016/S0022-1759(98)00065-9

Winandy M., Lewalle P., Deneys V., Ferrant A., De Bruyere M.

Improved IL-2 detection for determination of helper T lymphocyte precursor frequency in limiting dilution assay.

J. Immunol. Methods 215:81-94(1998)

 

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308

Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.

Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.

PLoS ONE 14:E0218412-E0218412(2019)