A2780细胞系

【A2780】A2780细胞/A2780细胞/A2780人卵巢癌细胞Cell line name A2780

Synonyms A-2780; 2780; A2780S; A2780par

Accession CVCL_0134

Resource Identification Initiative To cite this cell line use: A2780 (RRID:CVCL_0134)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: KuDOS 95 cell line panel.

Part of: MD Anderson Cell Lines Project.

Part of: OCCP ovarian cancer cell line panel.

Population: African American.

Doubling time: 25.3 +- 1 hours (PubMed=3539322); 16 hours (PubMed=25984343); 18.41 hours (JWGray panel).

Microsatellite instability: Instable (MSI-low) (PubMed=15677628; Sanger).

Omics: Array-based CGH.

Omics: CRISPR phenotypic screen.

Omics: Deep exome analysis.

Omics: Deep proteome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: Genome sequenced.

Omics: GPI-anchored proteins analysis by proteomics.

Omics: Metabolome analysis.

Omics: N-glycan profiling by lectin array.

Omics: Protein expression by reverse-phase protein arrays.

Omics: Proteome analysis by 2D-DE/MS.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Omics: Transcriptome analysis by serial analysis of gene expression (SAGE).

Derived from site: In situ; Ovary; UBERON=UBERON_0000992.

PubMed=23839242; DOI=10.1038/ncomms3126; PMCID=PMC3715866

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PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878

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Genome Med. 7:118.1-118.7(2015)

 

PubMed=26972028; DOI=10.1016/j.jprot.2016.03.008

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Identification of glycosylphosphatidylinositol-anchored proteins and omega-sites using TiO2-based affinity purification followed by hydrogen fluoride treatment.

J. Proteomics 139:77-83(2016)

 

PubMed=27141528; DOI=10.1016/j.dib.2016.04.001; PMCID=PMC4838930

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PubMed=27235858; DOI=10.1016/j.ygyno.2016.05.028; PMCID=PMC4961516

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Cell 166:740-754(2016)

 

PubMed=27561551; DOI=10.1038/ncomms12645; PMCID=PMC5007461

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Cancer Cell 31:225-239(2017)

 

PubMed=28273451; DOI=10.1016/j.celrep.2017.02.028

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PubMed=28546799; DOI=10.1186/s12014-017-9155-z; PMCID=PMC5442857

Zhao R., Qin W.-J., Qin R.-H., Han J., Li C., Wang Y.-S., Xu C.-J.

Lectin array and glycogene expression analyses of ovarian cancer cell line A2780 and its cisplatin-resistant derivate cell line A2780-cp.

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PubMed=30485824; DOI=10.1016/j.celrep.2018.10.096; PMCID=PMC6481945

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PubMed=30894224; DOI=10.1186/s40659-019-0220-0; PMCID=PMC6427839

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Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line.

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PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675

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PubMed=30971826; DOI=10.1038/s41586-019-1103-9

Behan F.M., Iorio F., Picco G., Goncalves E., Beaver C.M., Migliardi G., Santos R., Rao Y., Sassi F., Pinnelli M., Ansari R., Harper S., Jackson D.A., McRae R., Pooley R., Wilkinson P., van der Meer D.J., Dow D., Buser-Doepner C.A., Bertotti A., Trusolino L., Stronach E.A., Saez-Rodriguez J., Yusa K., Garnett M.J.

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Nature 569:503-508(2019)

 

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254

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Cell 180:387-402.e16(2020)

 

PubMed=33287223; DOI=10.3390/ijms21239218; PMCID=PMC7730278

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Transcriptome remodeling in gradual development of inverse resistance between paclitaxel and cisplatin in ovarian cancer cells.

Int. J. Mol. Sci. 21:9218.1-9218.30(2020)

 

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775

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