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Human IL-13 Recombinant Protei

n(PeproTech 200-13-2ug 现货特卖)
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  • Peprotech
  • 200-13-2ug
  • 2025年07月14日
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    • 库存

      大量

    • 保质期

      见COA

    • 供应商

      维百奥生物

     

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    维百奥生物库存现货,特价销售Human IL-13 Recombinant Protein 2ug

    | 产品信息

    品名:Human IL-13 Recombinant Protein

    品牌:Peprotech

    货号:200-13-2ug

    规格:2ug

     

    产品属性

    种属Human形式Lyophilized
    Expression SystemE. coli纯化类型purified
    分子量12.6 kDa内含物no preservative
    内毒素浓度<1 EU/µg保存条件-20°C
    偶联物Unconjugated运输条件Ambient
    已发表种属Human, Mouse, Non-human primate, Pig, Rat
    纯度≥ 98% by SDS-PAGE gel and HPLC analyses.
    氨基酸序列MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN
    活性The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg.

     

    产品描述

    Recombinant HumanIL-13 is a 12.6 kDa protein consisting of 115 amino acid residues.

     

    耙标信息

    IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

     

     

     

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