- 询价
- Agrisera
- Sweden
- AS21 4569
- 2026年01月07日
- ELISA (ELISA), Immunolocalisation (IL), Western blot (WB)
- Rabbit
- Human, Mouse and Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide corresponding to the human caspase 3 cleavage site, 6 aa (CGIETD) UniProt: P42574
- 形态：
Serum. Contains 0.05% sodium azide.
- 保存条件：
Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
- 适应物种：
Human, Mouse and Rat
- 供应商：
Agrisera
- 宿主：
Rabbit
- 应用范围：
ELISA (ELISA), Immunolocalisation (IL), Western blot (WB)
- 靶点：
Anti-ACP3 | Activated Caspase 3 (p20/p17 subunit)
- 抗体英文名：
Anti-ACP3 | Activated Caspase 3 (p20/p17 subunit)
- 抗体名：
Anti-ACP3 | Activated Caspase 3 (p20/p17 subunit)
- 规格：
100 µl
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文献和实验Cleavage by granzyme B, caspase-6, caspase-8 and caspase-10 generates the two active subunits. Additional processing of the propeptides is likely due to the autocatalytic activity of the activated protease. Active heterodimers between the small subunit
, TNF, DNA damage and ER stress. Fas and the TNFR activate caspases 8 and 10; DNA damage leads to the activation of caspase 9; and ER stress leads to the calcium-mediated activation of caspase 12. Anti-apoptotic ligands including growth factors
. Apo3L recruits initiator caspase 8 via the adapter protein FADD. Caspase 8 then oligomerizes and is activated via autocatalysis. Activated caspase 8 stimulates apoptosis via two parallel cascades: it directly cleaves and activates caspase
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