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Anti-UmuD | Protein UmuD

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  • 询价
  • Agrisera
  • Sweden
  • AS21 4546
  • 2026年01月06日
  • Western blot (WB)
  • Rabbit
  • Escherichia coli
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Highly purified, full length, recombinant UmuD protein from E.coli, UniProt: P0AG11

    • 形态

      Serum. Contains 0.05 % sodium azide.

    • 保存条件

      Store at -20°C and make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

    • 克隆性

      Polyclonal

    • 适应物种

      Escherichia coli

    • 供应商

      Agrisera

    • 宿主

      Rabbit

    • 应用范围

      Western blot (WB)

    • 靶点

      Anti-UmuD | Protein UmuD

    • 抗体英文名

      Anti-UmuD | Protein UmuD

    • 抗体名

      Anti-UmuD | Protein UmuD

    • 规格

      100 µl

    The products of umuD , umuC , and recA genes (SOS genes) are required for mutagenesis induced by radiation or chemical agents. Transcription of these SOS genes is repressed by a repressor, LexA protein in uninduced cells. Exposure of cells to DNA-damaging agents activates RecA protein to promote proteolytic cleavage of LexA protein. Inactivation of LexA protein by the cleavage consequently derepresses the SOS genes, umuD, C and recA . UmuD protein is then auto-cleaved, which is promoted by RecA protein ssDNA in a ATP-dependent manner. The processed UmuD protein is the active form for mutagenesis and the UmuD-UmuC complex functions as an error-prone translesion DNA polymerase.

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    图标文献和实验
    该产品被引用文献
    Shinagawa et al. (1998). RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis. Proc Natl Acad Sci U S A. 1988 Mar;85(6):1806-10. doi: 10.1073/pnas.85.6.1806. PMID: 3126496; PMCID: PMC279868.
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    • Yeast Two-Hybrid Screening for Proteins Interacting With the Anti-Apoptotic Protein A20

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    图标技术资料

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    Anti-UmuD | Protein UmuD
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