3-Nitropropionic acid

3-Nitropropionic Acid and Other Metabolic Toxin Lesions of the Striatum

and excitotoxicity-induced neurodegeneration, which have established cell death pathways in HD remain as mainstream platform for studying the disease. The focus of this book chapter is on the mitochondrial inhibitor 3-nitropropionic acid (3-NP). We previously

3-Nitropropionic Acid Model of Metabolic Stress: Assessment by Magnetic Resonance Imaging

3-Nitropropionic acid (3-NPA) is a potent mitochondrial inhibitor that can be administered systemically to create a progressive and localized striatal neurodegeneration mimicking many of the pathological features of Huntington’s disease

尿刊酸 urocanic acid

β-咪唑丙烯酸。给予狗大量的组氨酸后可从尿中得到，还有细菌作用于组氨酸也能生成尿刊酸。在哺乳类的肝脏或细菌中作为从组氨酸到谷氨酸的代谢途径的中间体，在组氨酸酶的作用下进行分子内的无氧脱氨基而生成。通常尿刊酸在肝脏酶（尿刊酸酶）的作用下进一步分解转变成谷氨酸。