Rabbit Polyclonal IRE1 alpha [

gene_symbol：ERN1
predicted_size：null
Uniprot ID：O7546
description：Rabbit Polyclonal IRE1 alpha [p Ser724] Antibody
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus by splicing XBP1 mRNA converting it into a potent unfolded-protein response transcriptional activator. It is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities. mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER.
immunogen：A synthetic peptide surrounding the phosphorylated serine 724 of the human IRE1 alpha protein. [Swiss-Prot #O75460]
recommended_dilution：WB: 1:1000, ELISA: 1:100-1:2000, IHC: 1:10-1:500, IHC-F: , IHC-P: 1:10-1:500
predicted_size：null
buffer：PBS, 0.01% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
host_species：Rabbit
applications：WB
reactivities：Human, Mouse, Rat, Rabbit (Does not react with: Primate)