OriGene CD8A Rabbit Monoclonal

ProductName：CD8A Rabbit Monoclonal Antibody [Clone ID: OTIR3D5]
description：CD8 Rabbit monoclonal antibody,clone OTIR3D5
symbol：CD8A
synonyms：CD8; Leu2; p32
locusid：925
Concentration：1.00mg/ml
sub_category：Primary Antibodies
uniprot_id：P01732
Applications：IHC
CNdelivery：2周
RecommendDilution：IHC 1:1600
Reactivity：Human
Immunogen：Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human CD8 (NP_001759). The exact sequence is proprietary.
Purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation：Unconjugated
ProteinFamilies：Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
ProteinPathways：Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway
GeneName：CD8a molecule
Background：The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
isotypes_filter：IgG
predicted_size：25.7 kDa