Purified recombinant protein o

gene_symbol：NF2
Description：Purified recombinant protein of Human neurofibromin 2 (merlin) (NF2), transcript variant 13, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Accn：NM_181831
Unipro ID：P35240
Synonyms：ACN; BANF; merlin-1; SCH
Species：Human
Amount：50 ug
Delivery time：2周
Expression sequence：A DNA sequence encoding human full-length NF2
Tags：N-His
PredictedMW：58.9 kDa
Buffer：50 mM Tris-HCl, pH 8.0, 8 M urea
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation
Endotoxin
Shipping
Background：This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008]