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- 详细信息
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- 文献和实验
- 技术资料
- 保存条件:
Store at -20˚C
- 英文名:
Recombinant Human Merlin(NF2)
- 库存:
详询
- 供应商:
南京莱富赛
- 规格:
详询
host_species:E.coli
purification:Greater than 85% as determined by SDS-PAGE.
other_names:Moesin-ezrin-radixin-like protein Neurofibromin-2 Schwannomerlin Schwannomin SCH
accession_no:P35240
calculated_mw:73.7 kDa
tag info:N-terminal 6xHis-tagged
Immunogen Description:Expression Region:1-595aa
Sequence Info:Full Length
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Probable regulator of the Hippo,SWH (Sav,Wts,Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo,SWH (Sav,Wts,Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP,DCAF1 E3 ubiquitin-protein ligase complex.
产品详细信息请点击:Recombinant Human Merlin(NF2)
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