Recombinant protein of human c

gene_symbol：HP1 gamma
Description：Recombinant protein of human chromobox homolog 3 (CBX3), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Accn：NM_007276
Unipro ID：Q13185
Synonyms：HECH; HP1-GAMMA; HP1Hs-gamma
Species：Human
Amount：50 ug
Delivery time：现货
Expression sequence：A DNA sequence encoding human full-length CBX3
Tags：N-His
PredictedMW：20.6 kDa
Buffer：25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation
Endotoxin
Shipping
Background：At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]