Purified recombinant protein o

gene_symbol：LIN28B
Description：Purified recombinant protein of Human lin-28 homolog B (C. elegans) (LIN28B), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Accn：NM_001004317
Unipro ID：Q6ZN17
Synonyms：CSDD2
Species：Human
Amount：50 ug
Delivery time：现货
Expression sequence：A DNA sequence encoding human full-length LIN28B
Tags：N-His
PredictedMW：26.9 kDa
Buffer：20 mM PB, pH 7.4
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation
Endotoxin
Shipping
Background：The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]