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Description:Recombinant protein of human caspase recruitment domain family, member 9 (CARD9), transcript variant 2, 20 µg
Accn:NM_052814
Unipro ID:Q9H257
Synonyms:CANDF2; hCARD9
Species:Human
Amount:20 ug
Delivery time:现货
Expression sequence:>RC225844 representing NM_052814 Red=Cloning site Green=Tags(s) MSDYENDDECWSVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRKVGVLLDILQR TGHKGYVAFLESLELYYPQLYKKVTGKEPARVFSMIIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSK DDFIKELRVKDSLLRKHQERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEI DQLKHSLMKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYI QVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRIEAILLQM EEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCEAQLLAVEGRLRRQQLET LVLSSDLEDGSPRRSQELSLPQDLEDTQLSDKGCLAGGGSPKQPFAALHQEQVLRNPHDAGPAGLPGIGA VC TRRLEQKLISEEDLAANDILDYKDDDDKV
Tags:C-Myc/DDK
PredictedMW:56.5 kDa
Buffer:25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Stability:Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>0.05 µg/µL as determined by microplate BCA method
Preparation:Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Endotoxin
Shipping
Background:The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. [provided by RefSeq, Jul 2008]
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文献和实验TRAF‐Mediated TNFR‐Family Signaling
conserved domain in CART1, a novel member of the tumor necrosis factor receptor‐associated protein family, which is expressed in breast carcinoma. J. Biol. Chem. 270:25715‐25721.
Introduction of human 14-3-3 proteins
of their association with the G-box DNA/protein complex by a monoclonal antibody screening approach.GF14 proteins are homologous to the 14-3-3 family of mammalian proteins.Here we demonstrate that recombinant GF14 omega,one member of the Arabidopsis GF14 protein family
like PKB. Proapoptotic proteins which can be phosphorylated and inhibited by PKB include BAD (BCL2 Antagonist of Cell Death), human Caspase9, and the forkhead family of transcription factors. PKB can also cause stimulation of NF-KappaB (Nuclear Factor-Kappa
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