Recombinant protein of human haptoglobin (HP), transcript variant 1, 20 µg

Recombinant protein of human h

aptoglobin (HP), transcript variant 1, 20 µg
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  • ¥2900
  • OriGene已认证
  • TP323612
  • 2025年10月22日
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    gene_symbol:Haptoglobin
    Description:Recombinant protein of human haptoglobin (HP), transcript variant 1, 20 µg
    Accn:NM_005143
    Unipro ID:P00738
    Synonyms:BP; HP2ALPHA2; HPA1S
    Species:Human
    Amount:20 ug
    Delivery time:4周
    Expression sequence:>RC223612 representing NM_005143 Red=Cloning site Green=Tags(s) MSALGAVIALLLWGQLFAVDSGNDVTDIADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRTEGDGVYTLND KKQWINKAVGDKLPECEADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGD KLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSE NATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQVDIGLIKLKQKVSVNERVMPICLPSKDYAEVGRVGY VSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDT CYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
    Tags:C-Myc/DDK
    PredictedMW:43.3 kDa
    Buffer:25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
    Stability:Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
    Bioactivity
    Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
    Concentration:>0.05 µg/µL as determined by microplate BCA method
    Preparation:Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
    Endotoxin
    Shipping
    Background:This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]

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