Recombinant protein of human E

gene_symbol：EP300
Description：Recombinant protein of human E1A binding protein p300 (EP300),residues 1066-1707,with C-terminal DDK tag,expressed in sf9 cells
Accn：NM_001429
Unipro ID：Q09472
Synonyms：KAT3B; MKHK2; p300; RSTS2
Species：Human
Amount：20 ug
Delivery time：现货
Expression sequence：A DNA sequence from TrueORF clone, [RC223265], encoding E1A binding domain(Tyr1066-Lys1707)of human EP300
Tags：C-DDK
PredictedMW：75 kDa
Buffer：50 mM Tris-HCl, pH 8.0, 150 mM NaCl, 20% glycerol
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation
Endotoxin
Shipping
Background：This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]