- ￥3290
- Abbiotec
- 美国
- 600294
- 2025年12月28日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
保存于-213℃
- 保质期：
一年
- 英文名：
Human Retinol Binding Protein
- 库存：
一定量库存
- 供应商：
美国ABBIOTEC公司
- 规格：
0.01 mg
Retinol binding protein (RBP) belongs to the lipocalin superfamily of proteins. RBP is synthesized and secreted by hepatic paraenchymal cells and is involved in the binding of retinol and transthyretin, preventing loss by glomerular filtration and renal excretion before transport to the peripheral tissues. Increased plasma levels of retinol binding protein have been shown to cause systemic insulin resistance, suggesting the protein plays a role in the pathogenesis of Type II diabetes. Recombinant RBP comprises a 183 amino acid fragment (19-201) corresponding to the mature RBP and is expressed in E. coli with an amino-terminal hexahistidine tag.
形 态 ：
Each vial contains 0.01 mg protein (liquid) in PBS pH7.4, 50% glycerol. Final concentration 0.1-1 mg/ml.
来 源 ：
E. coli
别 名 ：
Retinol Binding Protein; Plasma retinol binding protein 4 (RBP4); Interstitial retinol binding protein 4; RBP
纯 度 ：
Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
分子量 ：
25.57 kDa
应 用 ：E, WB
保存条件 ：
Store at -20°C. Product is guaranteed one year from the date of shipment.
产品链接 ：http://www.abbiotec.com/proteins/human-retinol-binding-protein
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文献和实验Expression and Mutagenesis of Retinol-Binding Protein
Vitamin A is transported in the plasma as retinol bound to a carrier protein, called retinol-binding protein (RBP), which itself forms a complex with the thyroxine-binding protein, known as transthyretin (TTR). This complex exists in equilibrium
Methods for Producing Recombinant Human Cellular Retinaldehyde-Binding Protein
The cellular retinaldehyde-binding protein (CRALBP) is expressed at high levels in vertebrate visual trssue, where it may serve to modulate the interaction of 11-cis -retinol with visual-cycle enzymes in the retinal pigment epithelium (RPE
Interactions of Retinol-Binding Protein with Transthyretin and Its Receptor
To study the interaction of retinol-binding protein (RBP) with its plasma carrier, transthyretin (TTR), spectrofluorimetry, and circular dichroism have previously been used. Both these techniques require milligram quantities of the proteins
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