Rabbit Polyclonal Anti-TLR2 An

gene_symbol：TLR2
predicted_size：90 kDa
Uniprot ID：O663
description：Rabbit Polyclonal Anti-TLR2 Antibody
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
immunogen：Fusion protein of human TLR2
recommended_dilution：WB: 500-2000 WB positive control: K562 cell lysate IHC: 50-200 Positive control: Human colorectal cancer Predicted cell location: Cell membrane or Cytoplasm
predicted_size：90 kDa
buffer：pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
host_species：Rabbit
applications：IHC, WB
reactivities：Human