Rabbit Polyclonal Anti-NINJ1 A

gene_symbol：NINJ1
predicted_size：Predicted: 17 kDa; Observed: 16 kDa
Uniprot ID：Q92982
description：Rabbit Polyclonal Anti-NINJ1 Antibody
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：Ninjurin-1 (NINJ1) is a homophilic adhesion molecule that is strongly induced in dorsal root ganglion (DRG) and Schwann cells following nerve injury and promotes neurite outgrowth of DRG neurons (1,2), suggesting that NINJ1 may play a role in nerve regeneration. NINJ1 is transcriptionally regulated by p53 and is induced by DNA damage in a p53-dependent manner. A deficiency of NINJ1 increases p53 expression, suppresses cell proliferation, but enhances apoptosis and premature senescence in a p53-dependent manner as well as radiation-induced cell mortality (3).
immunogen：NINJ1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human NINJ1.
recommended_dilution：IHC-P: 5 ug/ml IF: 20 ug/ml
predicted_size：Predicted: 17 kDa; Observed: 16 kDa
buffer：PBS containing 0.02% sodium azide.
host_species：Rabbit
applications：IF, IHC
reactivities：Human, Mouse, Rat