LXR alpha (NR1H3) Rabbit Monoc

ProductName：LXR alpha (NR1H3) Rabbit Monoclonal Antibody
description：LXR alpha Antibody
symbol：NR1H3
synonyms：Liver X receptor alpha; LXR a; LXRA; NR1H3; RLD1
locusid：10062
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：Q13133
Applications：FC, ICC/IF, WB
CNdelivery：2周
RecommendDilution：WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50
Reactivity：Human, Mouse, Rat
Immunogen：A synthesized peptide derived from human LXR alpha
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：nuclear receptor subfamily 1 group H member 3
Background：Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：50kDa