p63 (TP63) Rabbit Monoclonal A

ProductName：p63 (TP63) Rabbit Monoclonal Antibody
description：p63 Antibody
symbol：TP63
synonyms：EEC3; KET; LMS; p51; p73H; p73L; SHFM4; TA p63 alpha; TP63; tumor protein p63
locusid：8626
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：Q9H3D4
Applications：FC, ICC/IF, IHC, WB
CNdelivery：2周
RecommendDilution：WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200 FC 1:500
Reactivity：Human, Mouse, Rat
Immunogen：A synthesized peptide derived from human p63
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：tumor protein p63
Background：Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis.
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：77kDa