FOXO3 Rabbit Monoclonal Antibo

ProductName：FOXO3 Rabbit Monoclonal Antibody
description：FoxO3a Antibody
symbol：FOXO3
synonyms：AF6q21 protein; FKHRL1; Forkhead box protein O3; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FOXO3A
locusid：2309
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：O43524
Applications：ICC/IF, IHC, WB
CNdelivery：2周
RecommendDilution：WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Reactivity：Human
Immunogen：A synthesized peptide derived from human FoxO3a
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：forkhead box O3
Background：FoxO3a is a transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：90kDa