NUMB Rabbit Monoclonal Antibod

ProductName：NUMB Rabbit Monoclonal Antibody [Clone ID: R09-2I5]
description：NUMB Rabbit monoclonal Antibody
symbol：NUMB
synonyms：h-Numb; S171
locusid：8650
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P49757
Applications：IHC, IP, WB
CNdelivery：2周
RecommendDilution：WB: 1/1000
IHC: 1/200
IP: 1/20
Reactivity：Human, Mouse, Rat
Immunogen：Recombinant protein of human NUMB
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：NUMB, endocytic adaptor protein
Background：Swiss-Prot Acc.P49757.Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 71 kDa; Observed MW: 71 kDa