Tau (MAPT) Rabbit Monoclonal A

ProductName：Tau (MAPT) Rabbit Monoclonal Antibody [Clone ID: R07-8H4]
description：Phospho-Tau (Ser404) Rabbit monoclonal Antibody
symbol：MAPT
synonyms：DDPAC; FLJ31424; FTDP-17; MAPTL; MGC138549; MSTD; MTBT1; MTBT2; PHF-tau; PPND; TAU
locusid：4137
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P10636
Applications：WB
CNdelivery：2周
RecommendDilution：WB: 1/1000
Reactivity：Human, Rat
Immunogen：A synthetic phosphopeptide corresponding to residues surrounding Ser404 of human Tau (Phosphorylated)
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：microtubule associated protein tau
Background：Swiss-Prot Acc.P10636.Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 79 kDa; Observed MW: 50-80 kDa