![OriGene XBP1 Rabbit Monoclonal Antibody [Clone ID: OTIR10G1]](https://img1.dxycdn.com/p/s14/2025/0213/901/4431294255169799881.jpg)
- ￥4070
- OriGene
- TA594227
- 2025年12月15日
- Rabbit
- null
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- 详细信息
- 技术资料
- 保存条件：
Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
- 克隆性：
Monoclonal
- 适应物种：
null
- 供应商：
OriGene
- 宿主：
Rabbit
- 规格：
100 ul
ProductName：XBP1 Rabbit Monoclonal Antibody [Clone ID: OTIR10G1]
description：XBP1 Rabbit monoclonal antibody,clone OTIR10G1
symbol：XBP1
synonyms：TREB-5; TREB5; XBP-1; XBP2
locusid：7494
Concentration：1 mg/ml
sub_category：Primary Antibodies
uniprot_id：P17861
Applications：WB
CNdelivery：现货
RecommendDilution：WB1:2000
Reactivity：Human, Mouse
Immunogen：Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human XBP1 (NP_005071) . The exact sequence is proprietary.
Purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation：Unconjugated
ProteinFamilies：Transcription Factors
ProteinPathways：null
GeneName：X-box binding protein 1
Background：This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. [provided by RefSeq, Jul 2008]
Buffer：PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
isotypes_filter：IgG
predicted_size：28.7KD
description：XBP1 Rabbit monoclonal antibody,clone OTIR10G1
symbol：XBP1
synonyms：TREB-5; TREB5; XBP-1; XBP2
locusid：7494
Concentration：1 mg/ml
sub_category：Primary Antibodies
uniprot_id：P17861
Applications：WB
CNdelivery：现货
RecommendDilution：WB1:2000
Reactivity：Human, Mouse
Immunogen：Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human XBP1 (NP_005071) . The exact sequence is proprietary.
Purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation：Unconjugated
ProteinFamilies：Transcription Factors
ProteinPathways：null
GeneName：X-box binding protein 1
Background：This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. [provided by RefSeq, Jul 2008]
Buffer：PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
isotypes_filter：IgG
predicted_size：28.7KD
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OriGene XBP1 Rabbit Monoclonal Antibody [Clone ID: OTIR10G1]
￥4070
