Galectin 3 (LGALS3) Rabbit Mon

ProductName：Galectin 3 (LGALS3) Rabbit Monoclonal Antibody [Clone ID: R05-8J4]
description：Galectin 3 Rabbit monoclonal Antibody
symbol：LGALS3
synonyms：CBP35; GAL3; GALBP; GALIG; L-31; LGALS2; MAC-2; MAC2
locusid：3958
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P17931
Applications：IHC, WB
CNdelivery：2周
RecommendDilution：WB: 1/1000
IHC: 1/2000
Reactivity：Human, Mouse, Rat
Immunogen：A synthetic peptide of human Galectin 3
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：lectin, galactoside binding soluble 3
Background：Swiss-Prot Acc.P17931.Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis . In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 26 kDa; Observed MW: 28 kDa