- ￥2310 - 15480
- Sino Biological
- 北京
- 10041-H03H
- 2025年08月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human CD137 / 4-1BB / TNFRSF9 Protein (His & Fc Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/100.00 µg/200.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥15480.0 |
|---|---|---|---|
| 规格： | 100.00 µg | 产品价格： | ￥2310.0 |
| 规格： | 200.00 µg | 产品价格： | ￥3870.0 |
4-1BB/CD137重组蛋白|Recombinant Human CD137 / 4-1BB / TNFRSF9 Protein (His & Fc Tag)（产品说明）
蛋白名称：Human CD137 / 4-1BB / TNFRSF9 Protein (His & Fc Tag)
蛋白构建：A DNA sequence encoding the N-terminal fragment (Met 1-Gln 186) of the extracellular domain of human 4-1BB (NP_001552.2) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：Measured by its binding ability in a functional ELISA. Immobilized 4-1BB-Fch (Cat:10041-H03H) at 10 μg/ml(100 μl/well) can bind TNFSF9/Biotin (Cat:15693-H01H), The EC50 of TNFSF9/Biotin (Cat:15693-H01H) is 20-60 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Gln 25
蛋白分子量：The recombinant human 4-1BB/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 409 amino acids and has a calculated molecular mass of 45.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh4-1BB/Fc monomer is approximately 60-65 kDa due to glycosylation.
蛋白NP号：NP_001552.2
蛋白氨基酸序列：Met1-Gln186
蛋白名称：Human CD137 / 4-1BB / TNFRSF9 Protein (His & Fc Tag)
蛋白构建：A DNA sequence encoding the N-terminal fragment (Met 1-Gln 186) of the extracellular domain of human 4-1BB (NP_001552.2) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：Measured by its binding ability in a functional ELISA. Immobilized 4-1BB-Fch (Cat:10041-H03H) at 10 μg/ml(100 μl/well) can bind TNFSF9/Biotin (Cat:15693-H01H), The EC50 of TNFSF9/Biotin (Cat:15693-H01H) is 20-60 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Gln 25
蛋白分子量：The recombinant human 4-1BB/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 409 amino acids and has a calculated molecular mass of 45.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh4-1BB/Fc monomer is approximately 60-65 kDa due to glycosylation.
蛋白NP号：NP_001552.2
蛋白氨基酸序列：Met1-Gln186
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文献和实验该产品被引用文献
1, Yi L, et al. Human and Mouse CD137 Have Predominantly Different Binding CRDs to Their Respective Ligands.PloS one, PubMed ID: 24466035
2, Yi L, et al. CD137-CRDI is not necessary in the role of contacting its natural ligand.Immunology and cell biology, PubMed ID: 27430526
2, Yi L, et al. CD137-CRDI is not necessary in the role of contacting its natural ligand.Immunology and cell biology, PubMed ID: 27430526
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4-1BB/CD137重组蛋白|Recombinant Human CD137 / 4-1BB / TNFRSF9 Protein (His & Fc Tag)
￥2310 - 15480
