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- 详细信息
- 技术资料
- 免疫原:
Recombinant protein of human E-cadherin
- 亚型:
Cell junction,Cell membrane,Endosome,Golgi apparatus,Single-pass type I membrane protein,trans-Golgi network
- 形态:
液体
- 保存条件:
Store at -20℃.Avoid freeze/thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,SAlexa Fluor 350,SAlexa Fluor 405,SAlexa Fluor 488,SAlexa Fluor 532,SAlexa Fluor 555,SAlexa Fluor 568,SAlexa Fluor 594,SAlexa Fluor 633,SAlexa Fluor 640,SAlexa Fluor 647,SAlexa Fluor 660,SAlexa Fluor 680,SAlexa Fluor 750
- 适应物种:
Mouse ; Human ; Rat
- 保质期:
咨询
- 抗原来源:
Recombinant protein of human E-cadherin
- 目录编号:
K011556P
- 级别:
实验级别
- 库存:
咨询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
IF
- 浓度:
WB 1:20000-200000. IHC 1:5000-20000. IF 1:50-800. IP 0.5-4.0ug.
- 靶点:
E-cadherin
- 抗体英文名:
Anti-E-cadherin Polyclonal Antibody
- 抗体名:
Anti-E-cadherin Polyclonal Antibody
- 规格:
50ul/100ul
| 规格: | 50ul | 产品价格: | ¥2650.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥4300.0 |
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.

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