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- 英文名:
IgA1, Immunoglobulin A1, Human Myeloma Plasma
Athens专注人源蛋白40年:
- In normal adult serum, the approximate percentage composition of IgA with respect to is subclasses is IgA1:90% and IgA2:10%. In secretory IgA, the subclass proportions may approach 50:50. The clinical significance of the subclasses has yet to be determined.

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文献和实验
Detection of Chromosome Abnormalities Using Cytoplasmic Immunoglobulin Staining and FISH in Myeloma
The low proliferation rate of myeloma cells in vitro can result in a normal cytogenetic karyotype with the abnormal cell population not being detected. Because plasma cell myeloma is a patchy disease, conventional FISH is also hampered
Purification and Characterization of Human Serum and Secretory IgA1 and IgA2 Using Jacalin
Human immunoglobulin A (IgA) is found in serum and secretions in several different forms (1 ), Serum IgA is produced by the bone marrow and is pre-dominately monomeric (M r = 160 kDa
Multiple myeloma is a hematological malignancy characterized by an increased number of bone marrow plasma cells and the presence of high levels of a serum monoclonal immunoglobulin that is coded by a unique genetic sequence in the variable










