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- abinscience
- France
- HB952073
- 2026年03月03日
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG2a, kappa
- 形态：
Liquid
- 保存条件：
0.01M PBS, pH 7.4.
- 克隆性：
Monoclonal
- 适应物种：
Human
- 保质期：
1 year
- 抗原来源：
Mouse
- 目录编号：
HB952073
- 级别：
科研级别
- 库存：
999
- 供应商：
abinscience
- 浓度：
1mg/ml
- 抗体英文名：
Anti-Phospho-γ-H2AX (pS139) Antibody (9F3)
- 抗体名：
Anti-Phospho-γ-H2AX (pS139) Antibody (9F3)
- 规格：
50ug
| Product name | Anti-Phospho-γ-H2AX (pS139) Antibody (9F3) |
|---|---|
| Catalog No. | HB952073 |
| Host species | Mouse |
| Specificity | \ |
| Conjugation | \ |
| Species reactivity | Human |
| Immunogen | \ |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Purity | >95% as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | IgG2a, kappa |
| Applications | IHC, WB |
| Target | H2a/x, Histone H2A.X, H2AFX, Histone H2AX, H2AX |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P16104 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | \ |
| Alternative Names | \ |
| Clone ID | \ |
| Species | \ |
| Note | For research use only. |
Abinscience, founded in 2023 and located in the innovation technology center in Strasbourg, France, is the core research reagent brand of ProteoGenix. Focusing on the development and production of life science research reagents, Abinscience takes "Empowering Bioscience Discovery" as its vision, and is committed to providing high-quality and innovative biological reagent products and technical solutions for global researchers.
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文献和实验from the block they synchronously progress through S, G2 , and M. We recently reported that exposure of cells to these inhibitors at concentrations commonly used to synchronize cell populations led to phosphorylation of histone H2AX on Ser 139 (induction of γH2AX
-H2AX Detection in Peripheral Blood Lymphocytes, Splenocytes, Bone Marrow, Xenografts, and Skin
, environmental effects, and aging, as well as in the clinic. DSBs can be detected in the nuclei of cultured cells and tissues with an antibody to H2AX phosphorylated on serine residue 139 (γ-H2AX). DSB levels can be obtained
的 相互作用，并充当效应蛋白的平台，导致下游级联事件。 磷酸化发生在所有核心组蛋白上，并且对每一个核心组蛋白都有不同的作用。组蛋白 H3 在丝氨酸 10 和 28 上的磷酸化，以及组蛋白 H2A 在 T120 上的磷酸化参与了染色质致密化以及有丝分裂过程中 染色质结构和功能的调节。这些是细胞周期和细胞生长的重要标志，在真核生物中得以保留。S139 处 H2AX 的磷酸化（产生 γH2AX）作为 DNA 损伤修复蛋白的招募点 (Lowndes et al., 2005, Pinto et al
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