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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Human
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
0.01M PBS,pH7.4.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
1 year
- 抗原来源:
Human
- 目录编号:
HF004336
- 级别:
科研级别
- 库存:
999
- 供应商:
abinscience
- 宿主:
Human
- 应用范围:
Research Grade Biosimilar
- 浓度:
1 mg/ml
- 靶点:
HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB
- 抗体英文名:
Research Grade Anti-Human EGFR/ERBB1/HER1 (KT112)
- 抗体名:
Research Grade Anti-Human EGFR/ERBB1/HER1 (KT112)
- 规格:
100ug

| Product name | Research Grade Anti-Human EGFR/ERBB1/HER1 (KT112) |
|---|---|
| Catalog No. | HF004336 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Endotoxin level | Please contact the lab for this information. |
| Expression system | Mammalian Cells |
| Accession | P00533 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -1272°C. |
| Alternative Names | KT112 |
| Species | \ |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
Abinscience, founded in 2023 and located in the innovation technology center in Strasbourg, France, is the core research reagent brand of ProteoGenix. Focusing on the development and production of life science research reagents, Abinscience takes "Empowering Bioscience Discovery" as its vision, and is committed to providing high-quality and innovative biological reagent products and technical solutions for global researchers.
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文献和实验隆抗体[14]。作用机制与MAB806相似。(4)MR1和Ua30:2MR1和Ua30:2是针对EGFRvIII缺失突变的基因融合区的ScFv。即针对合成含17氨基酸多肽(LEEKKGNYVVTDHSGGC)的单链抗体[15]。ScFv具有以下特点:良好的肿瘤组织穿透性、无交叉反应,副作用小,疗效高。四、展望由于EGFRvⅢ仅表达于肿瘤组织,它的特异性单抗就显示了良好的前景。目前基于EGFR的单克隆抗体研究较多且有的已应用于临床阶段,但大多为鼠源性,人抗鼠抗体(HAMA)产生不可避免。因此尽快制造出人鼠
) A431 cells. At 48 h after infection, these cells were stained with ten different primary antibodies (5 g/ml) specific for different cell surface markers: anti-CD15 (clone 2F3; BD, PharMingen, San Diego, CA), anti-ERBB-2 (clone SP77; ref. 5), anti-ERBB
肿瘤特异性染色体错误分离通过保持肿瘤异质性来控制癌症的可塑性
的Agilent Human Genome CGH 244 k Microarray服务。 非整倍体染色体的不稳定性是癌症的一大特点。研究者观察了由原代细胞培养出的神经胶质瘤细胞的7号染色体(Chr7)拷贝数变异(CNV)情况,发现普遍出现在胶质瘤中的Chr7-CNV的肿瘤异质性细胞。在高级别的胶质瘤(携带超过2个拷贝数的Chr7)中出现的百分比较低级别的胶质瘤更高。更有趣的是,由亲本培养出的所有的Chr7-非整倍体细胞形成的胶质瘤细胞系再现了由单细胞衍生的次生培养物。 研究人员随即探究了三个同系胶质
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