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- xy10001-MM08-P
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
常温，避光
- 克隆性：
单克隆
- 抗体名：
EGFR / HER1 / ErbB1 Antibody
Reagents : PE-conjugated mouse monoclonal antibody
Clone ID : 08
Ig Type : Mouse IgG1
Concentration : 2 μl/Test, 0.1 mg/ml
Formulation : Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation : This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human EGFR / HER1 / ErbB1 (rh EGFR / HER1 / ErbB1; Catalog#10001-H08H; NP_005219; Met 1-Ser 645) and conjugated with PE under optimum conditions, the unreacted PE was removed.
EGFR / HER1 / ErbB1 Antibody Background
As a member of the epidermal growth factor receptor tyrosine kinases subfamily, EGF R is a type Ⅰ transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR signaling plays a crucial role in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR homo- or hetero- dimerization, initiates subsequent tyrosine autophosphorylation and various downstream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling has been shown to exert actions on carcinogenesis and disease progression, and thus EGFR was proposed as a target for cancer therapy currently.
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xy-3058R phospho-Bim (Ser55)磷酸化细胞死亡调解子抗体
xy-3059R phospho-Bim (Ser69)磷酸化细胞死亡调解子抗体
xy-5134R BAG2Bcl-2结合抑凋亡蛋白2抗体
xym-0107M beta-Amyloid (1-42)β淀粉样肽1-42抗体
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xym-4713M beta-Amyloid (1-42)β淀粉样肽（1-42）单克隆抗体
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文献和实验人转录因子E2F1 ( E2F1 )ELISA 试剂盒 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 E2F1 单抗包被于酶标板上，标准品和样品中的 E2F1与单抗结合，加入生物素化的抗人 E2F1 ，形成免疫复合物连接在板上，辣根过氧化物酶标记的 Streptavidin 与生物素结合，加入底物工作液显蓝色，最后加终止液硫酸，在 450nm 处测 OD 值，E2F1 浓度与 OD 值成正比
Notes on Making Rat x Y3 Monoclonal Antibody Producing Hybridomas
Although Y3/Ag1.2.3 has its own myeloma light chain, their are numerous characteristics that make this a better parent line for making hybridomas than the 'Y0' chain loss variants or using NS0 to make rat x mouse hybrids. These are: a) Hybridomas
There is an increasing interest in the preparation of rat � rat hybridomas, because they have been found to be more stable in culture than mouse hybridomas and they secrete consistently high levels (10 �g/mL and above) of monoclonal antibody
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