- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- DMC100267
- 2025年07月14日
- Rabbit
- Human
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- 详细信息
- 技术资料
- 亚型：
Rabbit/Human Fc chimeric IgG1
- 形态：
Powder
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12个月
- 级别：
仅用于科研
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 宿主：
Rabbit
- 靶点：
TNFSF11
- 抗体英文名：
Anti-TNFSF11 antibody(DMC267); IgG1 Chimeric mAb
- 抗体名：
Anti-TNFSF11 antibody(DMC267); IgG1 Chimeric mAb
- 规格：
50μg
| SKU | DMC100267 |
|---|---|
| 产品分类 | Monoclonal Antibodies |
| 规格 | Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00 |
| 背景 | This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT:PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6; which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes; and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found. |
| Clone ID | DMC267 |
| 别名 | CD254; hRANKL2; ODF; OPGL; OPTB2; RANKL; sOdf; TNLG6B; TRANCE |
| 应用 | Flow Cyt |
| 形态与组成成分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 纯化方式 | Purified from cell culture supernatant by affinity chromatography |
| 反应种属 | Human |
| 推荐稀释比 | Flow Cyt 1:100 |
| 靶点 | TNFSF11 |
| Uniprot ID | O14788 |
Figure 1. Flow cytometry analysis with Anti-TNFSF11 (DMC267) on Expi293 cells transfected with human TNFSF11 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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TNFSF11抗体/Anti-TNFSF11 antibody(DMC267); IgG1 Chimeric mAb
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