- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- DMC100224
- 2025年07月14日
- Rabbit
- Human
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 亚型：
Rabbit/Human Fc chimeric IgG1
- 形态：
Powder
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12个月
- 级别：
仅用于科研
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 宿主：
Rabbit
- 靶点：
CD112
- 抗体英文名：
Anti-CD112 antibody(DMC224); IgG1 Chimeric mAb
- 抗体名：
Anti-CD112 antibody(DMC224); IgG1 Chimeric mAb
- 规格：
50μg
| SKU | DMC100224 |
|---|---|
| 产品分类 | Monoclonal Antibodies |
| 规格 | Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00 |
| 背景 | This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus; and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. |
| Clone ID | DMC224 |
| 别名 | NECTIN2; HVEB; PRR2; PVRL2; PVRR2 |
| 应用 | ELISA; Flow Cyt |
| 形态与组成成分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 纯化方式 | Purified from cell culture supernatant by affinity chromatography |
| 反应种属 | Human |
| 推荐稀释比 | ELISA 1:5000-10000; Flow Cyt 1:100 |
| 靶点 | CD112 |
| Uniprot ID | Q92692 |
Figure 1. CD112 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-CD112 (DMC224) on Expi293 cells transfected with human CD112 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
Figure 2. Flow cytometry analysis of antigen binding of anti-human CD112 mAb(DMC100224). (A) DMC100224 does not bind to MM.1S cells that do not express CD112. (B) A clear peak shift of DMC100224 was seen compared to the control when incubated with CD112-expressing MCF-7 cells, indicating strong binding of DMC100224 to CD112. Antibodies were incubated at 5 μg/mL.
Figure 3. Flow cytometry analysis of antigen binding of anti-human CD112 mAb(DMC100224). (A) DMC100224 does not bind to MM.1S cells that do not express CD112. (B) A clear peak shift of DMC100224 was seen compared to the control when incubated with CD112-expressing Huh7 cells, indicating strong binding of DMC100224 to CD112. Antibodies were incubated at 5 μg/mL.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验【翻译】Development trends for monoclonal antibody cancer therapeutics
(ADCC) and complement-dependent cytotoxicity (CDC), respectively, and are mediated through the Fc portion of mAbs. Some mAb isotypes (human IgG1 and IgG3, and murine IgG2a) are potentially more competent than others at inducing ADCC and CDC3, 26, 28
Preparation of Defined Human Embryonic Stem Cell Populations for Transcriptional Profiling
the same antigen is the antibody TG343 (Millipore, cat. no. MAB4346) PE rat anti‐mouse CD 90.2 (0.2 mg/ml; BD Pharmingen, cat. no. 553014)
【资源】全面归类网址：毕赤酵母表达各种来源蛋白（细菌，真菌，植物，人类等）
propeptideS, 10 mg/L, α-MF[215, 216]Cathepsin VS, α-MF[217]Cathepsin XS, 5 mg/L, α-MF, activable417CD14S, 20 mg/L,α-MF, active414, 550CD38S, 455 mg/L, α-MF[218]CD40 ligand soluble formS, 255 mg/L[219]CD140, solubleS, α-MF, functional522Chimeric B7-2 antibody
技术资料暂无技术资料 索取技术资料
