CD166抗体/Anti-CD166 antibody(DMC682); IgG1 Chimeric mAb

CD166抗体/Anti-CD166 antibody(DM

C682); IgG1 Chimeric mAb
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  • 询价
  • DIMA BIOTECH/缔码生物
  • 武汉
  • DMC100682
  • 2025年07月11日
  • Rabbit
  • Human
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    • 详细信息
    • 技术资料
    • 亚型

      Rabbit/Human Fc chimeric IgG1

    • 形态

      Powder

    • 保存条件

      Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      Human

    • 保质期

      12个月

    • 级别

      仅用于科研

    • 库存

      In Stock

    • 供应商

      缔码生物(武汉)科技有限公司

    • 宿主

      Rabbit

    • 靶点

      CD166

    • 抗体英文名

      Anti-CD166 antibody(DMC682); IgG1 Chimeric mAb

    • 抗体名

      Anti-CD166 antibody(DMC682); IgG1 Chimeric mAb

    • 规格

      50μg

    SKU DMC100682
    产品分类 Monoclonal Antibodies
    规格 Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
    背景 This gene encodes activated leukocyte cell adhesion molecule (ALCAM); also known as CD166 (cluster of differentiation 166); which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6; and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq; Aug 2011]
    Clone ID DMC682
    别名 CD166; MEMD
    应用 Flow Cyt
    形态与组成成分 Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
    纯化方式 Purified from cell culture supernatant by affinity chromatography
    反应种属 Human
    推荐稀释比 Flow Cyt 1:100
    靶点 CD166
    Uniprot ID Q13740-1

    DMC100682-CD166-Fig.1-FC-1.jpg

    Figure 1. CD166 protein is expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-CD166 (DMC682) on Expi293 cells transfected with human CD166 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

    dmc100682-cd166-fc2.jpg

    Figure 2. Flow cytometry analysis of antigen binding of anti-human CD166 mAb(DMC100682). (A) DMC100682 does not bind to K562 cells that do not express CD166. (B) A clear peak shift of DMC100682 was seen compared to the control when incubated with CD166-expressing Hela cells, indicating strong binding of DMC100682 to CD166. Antibodies were incubated at 5 μg/mL.

    dmc100682-cd166-fc3.jpg

    Figure 3. Flow cytometry analysis of antigen binding of anti-human CD166 mAb(DMC100682). (A) DMC100682 does not bind to K562 cells that do not express CD166. (B) A clear peak shift of DMC100682 was seen compared to the control when incubated with CD166-expressing Huh7 cells, indicating strong binding of DMC100682 to CD166. Antibodies were incubated at 5 μg/mL.

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