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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
Rabbit/Human Fc chimeric IgG1
- 形态:
Liquid
- 保存条件:
Store at 2°C-8°C for 6 months
- 克隆性:
Monoclonal
- 标记物:
PE-conjugated
- 适应物种:
Human
- 保质期:
12个月
- 级别:
仅用于科研
- 库存:
Under Development
- 供应商:
缔码生物(武汉)科技有限公司
- 宿主:
Rabbit
- 靶点:
CDH3
- 抗体英文名:
PE-conjugated Anti-CDH3 antibody(6A10); IgG1 Chimeric mAb
- 抗体名:
PE-conjugated Anti-CDH3 antibody(6A10); IgG1 Chimeric mAb
- 规格:
100test
| SKU | DMC101041P |
|---|---|
| 产品分类 | Monoclonal Antibodies |
| 规格 | Price: 100 test ¥3880.00 |
| 背景 | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015] |
| Clone ID | 6A10 |
| 别名 | CDHP;HJMD;PCAD |
| 应用 | Flow Cyt |
| 形态与组成成分 | Liquid,PBS with 0.05% Proclin300, 1% BSA |
| 纯化方式 | Purified from cell culture supernatant by affinity chromatography |
| 反应种属 | Human |
| 推荐稀释比 | Flow Cyt 1:100 |
| 靶点 | CDH3 |
| Uniprot ID | P22223 |
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文献和实验Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
【翻译】Development trends for monoclonal antibody cancer therapeutics
antigens are targeted, the response should ultimately lead to destruction of the targeted cell. The mode of destruction can be direct (for example, via conjugated radioactive isotopes or toxins, or antibody triggered apoptosis) or indirect (for example
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