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- 湖北省武汉市
- Human HSD17B4重组蛋白表达
- 2025年07月09日
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- 详细信息
- 文献和实验
- 技术资料
- 服务名称：
大肠杆菌系统重组蛋白表达
- 提供商：
普健生物（武汉）科技有限公司
Uniprot号：P51659
基因名：HSD17B4
蛋白名：Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)]
蛋白别名：
Peroxisomal multifunctional enzyme type 2, MFE-2, 17-beta-hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, D-bifunctional protein, DBP, Multifunctional protein 2, MFP-2, Short chain dehydrogenase/reductase family 8C member 1, (3R)-hydroxyacyl-CoA dehydrogenase, 1.1.1.n12, Enoyl-CoA hydratase 2, 4.2.1.107, 4.2.1.119, 3-alpha7-alpha12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase
服务内容：
| 服务项目 | 客户提供 | 服务内容 | 服务周期 | 交付内容 |
|---|---|---|---|---|
| 大肠杆菌系统 蛋白表达 | 基因序列 | 方案沟通 | 1天 | 方案报告 |
| 密码子优化和基因合成 | 5天 | 基因合成报告 | ||
| 表达纯化测试 | 3天 | 表达纯化测试报告 | ||
| 1L表达及纯化 | 3天 | 蛋白样品(3-5mg)及报告 | ||
| 放大发酵及纯化 | 7天 | 纯化的蛋白及报告 |
案例展示：
HSD17B4相关研究文献：
1. HSD17B4 methylation enhances glucose dependence of BT-474 breast cancer cells and increases lapatinib sensitivity. [37378696]
2. Genetics of ovarian insufficiency and defects of folliculogenesis. [34794894]
3. Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer. [32678070]
4. The Peroxisomal Localization of Hsd17b4 Is Regulated by Its Interaction with Phosphatidylserine. [33935042]
5. Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomes. [31176039]
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