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- 文献和实验
- 技术资料
- 抗体名:
InVivoMAb Anti-Human CD49d/ITGA4 Antibody (Iv0201)
- 抗体英文名:
InVivoMAb Anti-Human CD49d/ITGA4 Antibody (Iv0201)
- 浓度:
1 mg/ml
- 应用范围:
ELISA, Neutralization
- 宿主:
Human
- 适应物种:
Human
- 保质期:
1 year
- 级别:
科研级
- 库存:
999
- 供应商:
AntibodySystem
- 克隆性:
Monoclonal
- 亚型:
IgG1, kappa
- 规格:
100ug

| 宿主 | Human |
| 种属反应性 | Human |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 浓度 | 1 mg/ml |
| 纯度 | >95% as determined by SDS-PAGE. |
| 克隆类型 | Monoclonal |
| 同种型 | IgG1, kappa |
| 应用 | ELISA, Neutralization |
| 靶标 | ITGA4, CD49d, CD49 antigen-like family member D, CD49D, VLA-4 subunit alpha, Integrin alpha-IV, Integrin alpha-4 |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | Please contact with the lab for this information. |
| Accession号 | P13612 |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 克隆号 | Iv0201 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
AntibodySystem products span research areas including 48 viruses, superbugs, parasites, cancer, Alzheimer's, Parkinson's, allergic and hypersensitivity reactions, immune suppression, and immune activation.
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文献和实验ITGA4(CD49D)信号通路、病理作用与靶向治疗药物研究梳理
整合素alpha 4(ITGA4),又称CD49D,是整合素家族的关键亚基。它通过与β1或β7亚基结合,形成功能性异二聚体α4β1(VLA-4)和α4β7,在免疫细胞的黏附、运输及迁移中扮演核心角色。VLA-4还能介导白细胞在活化内皮细胞上的聚集。鉴于ITGA4在多发性硬化、炎症性肠病等多种自身免疫性疾病的病理过程中发挥关键作用,它已成为治疗干预的重要靶点。 ITGA4的表达分布 ITGA4主要分布于巨核细胞、红细胞、干细胞、NK细胞以及T细胞中。在T细胞亚群中,CD49D主要在CD
Introduction of human 14-3-3 proteins
of the tryptic peptides derived from the purified enzyme revealed two amino acid sequences homologous to the 14-3-3 proteins.A polyclonal antibody was raised against purified ST-IV.A 33 kDa protein was co-immunoprecipitated from rat brain extracts with the anti
Intracellular Cytokine Staining Protocol
anti-cytokine antibodies with excess amounts of unlabeled antibody. Alternatively, recombinant cytokines can be used for blocking.eBioscience antibodies are available as Functional Grade (FG) Purified (sterile, endotoxin-tested, no azide), Purified
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