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Daratumumab ELISA Kit ELISA 试

剂盒
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  • ¥6768
  • AntibodySystem已认证
  • 0.31-5 μg/mL
  • 0.156 μg/ml
  • KDD80801
  • France
  • 2025年09月05日
    48h发货
    24h回复
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    • 详细信息
    • 用户评价
    • 文献和实验
    • 技术资料
    • 库存

      999

    • 供应商

      AntibodySystem

    • 检测范围

      0.31-5 μg/mL

    • 检测方法

      Colorimetric

    • 应用

      ELISA

    • 标记物

      HRP

    • 样本

      Plasma, Serum

    • 灵敏度

      0.156 μg/ml

    • 规格

      96T

    产品细节图片1

    检测方法Colorimetric
    样本类型Plasma, Serum
    实验类型Quantitative
    灵敏度104.76 ng/mL
    检测范围156.25 - 10,000 ng/mL
    回收率80-120%
    稳定性和存储When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20 ℃, the rest reagents should be store at 4℃.
    背景Daratumumab is human IgG1 monoclonal antibody to CD38, which is a transmembrane glycoprotein that is frequently overexpressed on cancer cells including multiple myeloma cells. The monoclonal antibody binds to the CD38 molecule and triggers cell apoptosis, probably as a result of antibody mediated cytotoxicity. Daratumumab has been evaluated in heavily pretreated patients with refractory multiple myeloma and shown overall response rates of higher than expected. Daratumumab was given accelerated approval in the United States in 2015 for use in multiple myeloma. Current indications are as therapy of patients with refractory multiple myeloma in combination with lenalidomide (or bortezomib) and dexamethasone or as monotherapy in patients who have failed at least three previous regimens. Daratumumab is available as a solution for intravenous infusion in single use vials of 100 mg in 5 mL or 400 mg in 20 mL (20 mg/mL). The recommended dose is 16 mg/kg intravenously every week for 8 to 9 weeks, and then every 2, 3 or 4 weeks based upon indications and other agents being used. Premedication with methylprednisolone is recommended. Side effects are common and can include infusion reactions, bone marrow suppression, fatigue, nausea and vomiting, diarrhea, muscle spasms, back pain, fever, cough, dyspnea, peripheral edema, peripheral neuropathy and upper respiratory infection. Rare, but potentially serious side effects include severe infusion reactions, neutropenia, thrombocytopenia and interference with cross matching and red blood cell antibody screening.
    别名HuMax-CD38, CAS: 945721-28-8
    运输2-8 ℃
    备注For Research Use Only.

    AntibodySystem was founded in 2019 in France as an independent brand entity focused on the research, development, and production of protein and antibody reagents in the life sciences field. Our mission is to provide high-quality protein and antibody products to life science researchers worldwide. AntibodySystem's extensive product range includes traditional polyclonal antibodies, classic housekeeping antibodies, tag antibodies, high-activity proteins, in vivo functional antibodies, low-background flow cytometry antibodies, high-specificity nanobodies, specialized small molecule antibodies, premium phospho-specific antibodies, DNA/RNA antibodies, PEG antibodies, and more—spanning over ten product series.Currently, AntibodySystem's product lines cover multiple research areas, including 500 types of viruses and superbugs, parasites, tumors, Alzheimer's disease, Parkinson's disease, hypersensitivity and allergic reactions, immune suppression, and immune activation

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      该产品被引用文献

      期刊信息:Journal of pharmaceutical and biomedical analysis vol. 255 (2025): 116627.

      作者:Li, Weiqiang et al. 

      标题:Quantification of serum daratumumab in multiple myeloma patients by LC-MS/MS, comparison with ELISA.

       

      引用详情:货号-KDD80801;品名-Daratumumab ELISA Kit  ELISA 试剂盒

      文献和实验图片1

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      研选
      Daratumumab ELISA Kit ELISA 试剂盒
      ¥6768