SNU16细胞

SNU-16/SNU-16细胞系/SNU-16细胞株/SNU-16人胃癌细胞

Cell line name SNU-16

Synonyms SNU16; NCI-SNU-16

Accession CVCL_0076

Resource Identification Initiative To cite this cell line use: SNU-16 (RRID:CVCL_0076)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: FGFR genetic alteration cell panel (ATCC TCP-1034).

Part of: MD Anderson Cell Lines Project.

Part of: MYC genetic alteration cell panel (ATCC TCP-1035).

Part of: Seoul National University (SNU) cell line collection.

Part of: TCGA-110-CL cell line panel.

Population: Korean.

Doubling time: 27 hours (ATCC=CRL-5974; PubMed=2158397; PubMed=29435981).

Microsatellite instability: Stable (MSS) (PubMed=10674020; Sanger).

Omics: Array-based CGH.

Omics: CRISPR phenotypic screen.

Omics: Deep exome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.

PubMed=1676761; DOI=10.1093/jnci/83.13.938

Kim J.-H., Takahashi T., Chiba I., Park J.-G., Birrer M.J., Roh J.K., De Lee H., Kim J.-P., Minna J.D., Gazdar A.F.

Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines.

J. Natl. Cancer Inst. 83:938-943(1991)

 

DOI=10.1016/B978-0-12-333530-2.50014-9

Sekiguchi M., Suzuki T.

Gastric tumor cell lines.

(In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.287-316; Academic Press; New York; USA (1994)

 

PubMed=8806092; DOI=10.1002/jcb.240630505

Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P., McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr., Carney D.N., Minna J.D., Mulshine J.L.

NCI-Navy Medical Oncology Branch cell line data base.

J. Cell. Biochem. Suppl. 24:32-91(1996)

 

PubMed=8806095; DOI=10.1002/jcb.240630508

Park J.-G., Gazdar A.F.

Biology of colorectal and gastric cancer cell lines.

J. Cell. Biochem. Suppl. 24:131-141(1996)

 

PubMed=10674020; DOI=10.1016/S0959-8049(99)00206-3

Ku J.-L., Yoon K.-A., Kim D.-Y., Park J.-G.

Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.

Eur. J. Cancer 35:1724-1729(1999)

 

PubMed=14720123; DOI=10.1042/bj20031408; PMCID=PMC1224061

Kim H.-P., Lee M.-S., Yu J., Park J.-A., Jong H.-S., Kim T.-Y., Lee J.W., Bang Y.-J.

TGF-beta1 (transforming growth factor-beta1)-mediated adhesion of gastric carcinoma cells involves a decrease in Ras/ERKs (extracellular-signal-regulated kinases) cascade activity dependent on c-Src activity.

Biochem. J. 379:141-150(2004)

 

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416

Ku J.-L., Park J.-G.

Biology of SNU cell lines.

Cancer Res. Treat. 37:1-19(2005)

 

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113

Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.

Signatures of mutation and selection in the cancer genome.

Nature 463:893-898(2010)

 

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662

Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.

Cancer Res. 70:2158-2164(2010)