RWPE1细胞

RWPE-1/RWPE-1细胞系/RWPE-1细胞株/RWPE-1人正常前列腺上皮细胞

Cell line name RWPE-1

Synonyms RWPE1

Accession CVCL_3791

Resource Identification Initiative To cite this cell line use: RWPE-1 (RRID:CVCL_3791)

Comments Group: Patented cell line.

Part of: ENCODE project common cell types; tier 3.

Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11609.

Population: Caucasian.

Doubling time: ~22 hours (PBCF).

Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).

Omics: DNA methylation analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.

Cell type: Epithelial cell of prostate; CL=CL_0002231.

PubMed=22275356; DOI=10.1074/jbc.M111.302547; PMCID=PMC3322861

Lynch T.P., Ferrer C.M., Jackson S.R., Shahriari K.S., Vosseller K., Reginato M.J.

Critical role of O-linked beta-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis.

J. Biol. Chem. 287:11070-11081(2012)

 

PubMed=25877200; DOI=10.1038/nature14397

Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.

A resource for cell line authentication, annotation and quality control.

Nature 520:307-311(2015)

 

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469

Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mir T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

A landscape of pharmacogenomic interactions in cancer.

Cell 166:740-754(2016)

 

PubMed=30305041; DOI=10.1186/s12885-018-4848-x; PMCID=PMC6180441

Jividen K., Kedzierska K.Z., Yang C.-S., Szlachta K., Ratan A., Paschal B.M.

Genomic analysis of DNA repair genes and androgen signaling in prostate cancer.

BMC Cancer 18:960.1-960.20(2018)

 

PubMed=30787054; DOI=10.1158/1055-9965.EPI-18-1132; PMCID=PMC6548687

Hooker S.E. Jr., Woods-Burnham L., Bathina M., Lloyd S., Gorjala P., Mitra R., Nonn L., Kimbro K.S., Kittles R.A.

Genetic ancestry analysis reveals misclassification of commonly used cancer cell lines.

Cancer Epidemiol. Biomarkers Prev. 28:1003-1009(2019)