HC11小鼠乳腺上皮细胞

【ATCC来源】HC11细胞、HC11细胞、HC11HC11[小鼠乳腺上皮细胞]

Cell line name    HC11
Synonyms    HC-11; HC11 Mammary Epithelium
Accession    CVCL_0288
Resource Identification Initiative    To cite this cell line use: HC11 (RRID:CVCL_0288)
Comments    Doubling time: ~50-80 hours (DSMZ=ACC-780).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin    Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy    Parent: CVCL_5731 (COMMA-D)
Children:
CVCL_5G41 (HC11-BC20)    CVCL_5G42 (HC11-BC44)    CVCL_0R13 (HC11-C24)
CVCL_0R14 (HC11-C4)    CVCL_B4FA (HC11/MV7)    CVCL_B4FB (HC11/Twist)
CVCL_B4FC (HC11/Wnt-1)
Sex of cell    Female
Age at sampling    1Y
Publications    
PubMed=3416834; DOI=10.1002/j.1460-2075.1988.tb03048.x; PMCID=PMC454494
Ball R.K., Friis R.R., Schoenenberger C.A., Doppler W., Groner B.
Prolactin regulation of beta-casein gene expression and of a cytosolic 120-kd protein in a cloned mouse mammary epithelial cell line.
EMBO J. 7:2089-2095(1988)

PubMed=12702582
Howe L.R., Watanabe O., Leonard J., Brown A.M.C.
Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation.
Cancer Res. 63:1906-1913(2003)

PubMed=19523745; DOI=10.1016/j.diff.2009.05.003
Perotti C., Wiedl T., Florin L., Reuter H., Moffat S., Silbermann M., Hahn M., Angel P., Shemanko C.S.
Characterization of mammary epithelial cell line HC11 using the NIA 15k gene array reveals potential regulators of the undifferentiated and differentiated phenotypes.
Differentiation 78:269-282(2009)