LMH

LMH/LMH细胞系/LMH细胞株/LMH鸡原发性肝癌细胞

Cell line name LMH

Synonyms Leghorn Male Hepatoma cell line

Accession CVCL_2580

Resource Identification Initiative To cite this cell line use: LMH (RRID:CVCL_2580)

Comments Group: Bird cell line.

Virology: Efficient cell line for duck hepatitis B virus (DHBV) DNA synthesis following transfection with viral constructs (PubMed=2352324).

Virology: Efficiently supports the replication of avian leukosis virus subgroup J (ALV-J) (PubMed=29720272).

Transformant: ChEBI; CHEBI:34873; N-nitrosodiethylamine (Diethylnitrosamine; DEN).

Derived from site: In situ; Liver; UBERON=UBERON_0002107.

Cell type: Epithelial cell; CL=CL_0000066.

Disease Chicken hepatoma (NCIt: C134558)

Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)

Breed/subspecies: White Leghorn L-M.

Hierarchy Children:

CVCL_A3FF (LMH serum-free suspension) CVCL_3465 (LMH/2A) CVCL_E0XC (Ubigene LMH MYH9 KO)

Sex of cell Male

Age at sampling 1Y4M

Category Cancer cell line

Web pages

Publications

PubMed=3607775

Kawaguchi T., Nomura K., Hirayama Y., Kitagawa T.

Establishment and characterization of a chicken hepatocellular carcinoma cell line, LMH.

Cancer Res. 47:4460-4464(1987)

 

PubMed=2330000; DOI=10.1210/mend-4-2-201

Binder R., MacDonald C.C., Burch J.B.E., Lazier C.B., Williams D.L.

Expression of endogenous and transfected apolipoprotein II and vitellogenin II genes in an estrogen responsive chicken liver cell line.

Mol. Endocrinol. 4:201-208(1990)

 

PubMed=2352324; DOI=10.1128/JVI.64.7.3249-3258.1990; PMCID=PMC249546

Condreay L.D., Aldrich C.E., Coates L., Mason W.S., Wu T.-T.

Efficient duck hepatitis B virus production by an avian liver tumor cell line.

J. Virol. 64:3249-3258(1990)

 

PubMed=10564780; DOI=10.1016/S0304-4165(99)00159-2

Kolluri S., Elbirt K.K., Bonkovsky H.L.

Heme biosynthesis in a chicken hepatoma cell line (LMH): comparison with primary chick embryo liver cells (CELC).

Biochim. Biophys. Acta 1472:658-667(1999)

 

PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022

Karger A., Bettin B., Lenk M., Mettenleiter T.C.

Rapid characterisation of cell cultures by matrix-assisted laser desorption/ionisation mass spectrometric typing.

J. Virol. Methods 164:116-121(2010)

 

PubMed=29720272; DOI=10.1186/s13567-018-0537-7; PMCID=PMC5932828

Li T.-F., Xie J., Lv L., Sun S., Dong X.-M., Xie Q., Liang G.-C., Xia C.-C., Shao H.-X., Qin A.-J., Ye J.-Q.

A chicken liver cell line efficiently supports the replication of ALV-J possibly through its high level viral receptor and efficient protein expression system.

Vet. Res. 49:41.1-41.5(2018)

 

PubMed=34737324; DOI=10.1038/s41598-021-00779-5; PMCID=PMC8569163

Lung O., Candlish R.C., Nebroski M., Kruckiewicz P., Buchanan C., Moniwa M.

High-throughput sequencing for species authentication and contamination detection of 63 cell lines.

Sci. Rep. 11:21657-21657(2021)