RF6A

Cell line name RF/6A

Accession CVCL_4552

Resource Identification Initiative To cite this cell line use: RF/6A (RRID:CVCL_4552)

Comments Group: Non-human primate cell line.

Problematic cell line: Probably misidentified. While originally thought to be an endothelial cell line, it has been shown to lack functional and transcriptomic characteristics of such cell type (PubMed=30508043).

Omics: Transcriptome analysis by RNAseq.

Derived from site: In situ; Fetal eye, choroid; UBERON=UBERON_0010312+UBERON_0001776.

Derived from site: In situ; Fetal eye, retina; UBERON=UBERON_0003072.

Species of origin Macaca mulatta (Rhesus macaque) (NCBI Taxonomy: 9544)

Hierarchy Children:

CVCL_J443 (RF/6A 135)

Sex of cell Sex unspecified

Age at sampling 64FD

Category Spontaneously immortalized cell line

Publications

PubMed=3771439; DOI=10.1007/BF02623517

Hu F.-N., Mah K., Teramura D.J.

Gossypol effects on cultured normal and malignant melanocytes.

In Vitro Cell. Dev. Biol. 22:583-588(1986)

 

PubMed=3102454; DOI=10.1007/BF02623586

Lou D.-A., Hu F.-N.

Specific antigen and organelle expression of a long-term rhesus endothelial cell line.

In Vitro Cell. Dev. Biol. 23:75-85(1987)

 

PubMed=27259688; DOI=10.3109/02713683.2016.1145234

Li R., Du J.-H., Chang Y.

Role of autophagy in hypoxia-induced angiogenesis of RF/6A cells in vitro.

Curr. Eye Res. 41:1566-1570(2016)

 

PubMed=30508043; DOI=10.1167/iovs.18-25215; PMCID=PMC6278239

Makin R.D., Apicella I., Nagasaka Y., Kaneko H., Turner S.D., Kerur N., Ambati J., Gelfand B.D.

RF/6A chorioretinal cells do not display key endothelial phenotypes.

Invest. Ophthalmol. Vis. Sci. 59:5795-5802(2018)