ID8

ID8/ID8细胞系/ID8细胞株/ID8小鼠卵巢癌细胞

Cell line name ID8

Synonyms ID8/MOSEC

Accession CVCL_IU14

Resource Identification Initiative To cite this cell line use: ID8 (RRID:CVCL_IU14)

Comments Characteristics: Physiologically and biologically closely resembles human epithelial ovarian cancer.

Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.

Cell type: Epithelial cell of ovary; CL=CL_2000064.

Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)

Breed/subspecies: C57BL/6.

Hierarchy Children:

CVCL_VA22 (ID8-B7H6) CVCL_IU15 (ID8-Fluc) CVCL_C8UV (ID8-Luc)

CVCL_IU16 (ID8-Luc2) CVCL_E0W3 (Ubigene ID8 Arid1a KO) CVCL_E0W4 (Ubigene ID8 Atrx KO)

CVCL_E0W5 (Ubigene ID8 Fat1 KO) CVCL_E0W6 (Ubigene ID8 Hk2 KO) CVCL_E0W7 (Ubigene ID8 Kmt2c KO)

CVCL_E0W8 (Ubigene ID8 Kmt2d KO) CVCL_E0W9 (Ubigene ID8 Rb1 KO) CVCL_E0WA (Ubigene ID8 Smarca4 KO)

Sex of cell Female

Age at sampling Adult

Category Spontaneously immortalized cell line

STR profile Source(s): Millipore=SCC145; Ubigene=YC-C103

 

Markers:

Mouse STR 1-1 16

Mouse STR 1-2 20

Mouse STR 2-1 16

Mouse STR 3-2 14

Mouse STR 4-2 19.3

Mouse STR 5-5 17

Mouse STR 6-4 18

Mouse STR 6-7 15

Mouse STR 7-1 26.2

Mouse STR 8-1 18

Mouse STR 11-2 16

Mouse STR 12-1 17

Mouse STR 13-1 17

Mouse STR 15-3 22.3

Mouse STR 17-2 15

Mouse STR 18-3 17

Mouse STR 19-2 13

Mouse STR X-1 27

 

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Publications

PubMed=10753190; DOI=10.1093/carcin/21.4.585

Roby K.F., Taylor C.C., Sweetwood J.P., Cheng Y., Pace J.L., Tawfik O., Persons D.L., Smith P.G., Terranova P.F.

Development of a syngeneic mouse model for events related to ovarian cancer.

Carcinogenesis 21:585-591(2000)

 

PubMed=16886597

Janat-Amsbury M.M., Yockman J.W., Anderson M.L., Kieback D.G., Kim S.W.

Comparison of ID8 MOSE and VEGF-modified ID8 cell lines in an immunocompetent animal model for human ovarian cancer.

Anticancer Res. 26:2785-2789(2006)

 

PubMed=18036641; DOI=10.1016/j.ygyno.2007.10.035

Greenaway J., Moorehead R., Shaw P., Petrik J.

Epithelial-stromal interaction increases cell proliferation, survival and tumorigenicity in a mouse model of human epithelial ovarian cancer.

Gynecol. Oncol. 108:385-394(2008)

 

PubMed=27235858; DOI=10.1016/j.ygyno.2016.05.028; PMCID=PMC4961516

Hernandez L., Kim M.K., Lyle L.T., Bunch K.P., House C.D., Ning F., Noonan A.M., Annunziata C.M.

Characterization of ovarian cancer cell lines as in vivo models for preclinical studies.

Gynecol. Oncol. 142:332-340(2016)