SNU-1
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      T25

    SNU-1/SNU-1细胞系/SNU-1细胞株/SNU-1人胃癌细胞

    Cell line name SNU-1

    Synonyms SNU1; NCI-SNU-1

    Accession CVCL_0099

    Resource Identification Initiative To cite this cell line use: SNU-1 (RRID:CVCL_0099)

    Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

    Part of: COSMIC cell lines project.

    Part of: MD Anderson Cell Lines Project.

    Part of: Seoul National University (SNU) cell line collection.

    Population: Korean.

    Doubling time: 26 hours (ATCC=CRL-5971; PubMed=2158397; PubMed=29435981).

    Microsatellite instability: Instable (MSI-high) (PubMed=10674020; PubMed=31068700; Sanger).

    Omics: Array-based CGH.

    Omics: CRISPR phenotypic screen.

    Omics: Deep exome analysis.

    Omics: Deep quantitative proteome analysis.

    Omics: DNA methylation analysis.

    Omics: Protein expression by reverse-phase protein arrays.

    Omics: SNP array analysis.

    Omics: Transcriptome analysis by microarray.

    Omics: Transcriptome analysis by RNAseq.

    Derived from site: In situ; Stomach; UBERON=UBERON_0000945.

    PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027

    Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

    The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

    Nature 483:603-607(2012)

     

    PubMed=24807215; DOI=10.1038/ncomms4830; PMCID=PMC4024760

    Liu J.-F., McCleland M.L., Stawiski E.W., Gnad F., Mayba O., Haverty P.M., Durinck S., Chen Y.-J., Klijn C., Jhunjhunwala S., Lawrence M., Liu H.-B., Wan Y.-N., Chopra V.S., Yaylaoglu M.B., Yuan W.-L., Ha C., Gilbert H.N., Reeder J., Pau G., Stinson J., Stern H.M., Manning G., Wu T.D., Neve R.M., de Sauvage F.J., Modrusan Z., Seshagiri S., Firestein R., Zhang Z.-M.

    Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.

    Nat. Commun. 5:3830.1-3830.8(2014)

     

    PubMed=25343454; DOI=10.1371/journal.pone.0111146; PMCID=PMC4208810

    Choong M.-L., Tan S.-H., Tan T.-Z., Manesh S., Ngo A., Yong J.W.-Y., Yang H.H., Lee M.A.

    Molecular integrative clustering of Asian gastric cell lines revealed two distinct chemosensitivity clusters.

    PLoS ONE 9:E111146-E111146(2014)

     

    PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981

    Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.

    A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.

    OncoImmunology 3:e954893.1-e954893.12(2014)

     

    PubMed=25485619; DOI=10.1038/nbt.3080

    Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.

    A comprehensive transcriptional portrait of human cancer cell lines.

    Nat. Biotechnol. 33:306-312(2015)

     

    PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878

    Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.

    TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

    Genome Med. 7:118.1-118.7(2015)

     

    PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469

    Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mir T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

    A landscape of pharmacogenomic interactions in cancer.

    Cell 166:740-754(2016)

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    *发表【中文论文】请标注:由上海酶研生物科技有限公司提供;

    *发表【英文论文】请标注:From Shanghai EK-Bioscience Biotechnology Co., Ltd.

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