BT-B

【BT-B】BT-B细胞/BT-B细胞/BT-B人膀胱癌细胞Cell line name BT-B [Human HeLa contaminated cell line]

Accession CVCL_1858

Resource Identification Initiative To cite this cell line use: BT-B [Human HeLa contaminated cell line] (RRID:CVCL_1858)

Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (DSMZ=ACC-227). Originally thought to originate from the a 66 year old Caucasian man with a malignant urinary bladder carcinoma.

Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00394.

Population: African American.

Doubling time: ~43 hours (DSMZ=ACC-227).

Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).

Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.

PubMed=2108047; DOI=10.1016/0014-4827(90)90080-T

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Density-dependent tumor cell death and reversible cell cycle arrest: mutually exclusive modes of monocyte-mediated growth control.

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Dissecting the immunobiological effects of Bacillus Calmette-Guerin (BCG) in vitro: evidence of a distinct BCG-activated killer (BAK) cell phenomenon.

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PubMed=11668190; DOI=10.1177/002215540104901105

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Immunocytochemical analysis of cell lines derived from solid tumors.

J. Histochem. Cytochem. 49:1369-1378(2001)

 

PubMed=25877200; DOI=10.1038/nature14397

Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.

A resource for cell line authentication, annotation and quality control.

Nature 520:307-311(2015)