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- 2026年02月22日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
联科生物
- 规格：
10ug/50ug/100ug
| 规格： | 10ug | 产品价格： | ￥700.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥2500.0 |
| 规格： | 100ug | 产品价格： | ￥3300.0 |
| SOURCE |
Escherichia coli |
|---|---|
| SYNONYMS |
Interleukin 1 beta; IL1F2; IL-1B; IL1-BETA |
| ACCESSION |
P10749 |
| MOLECULAR MASS |
17.5 KDa |
| DESCRIPTION |
Recombinant Mouse IL-1 beta is an 17.5 kDa protein consisting of 153 amino acid residues. |
| SHIPPING |
The product is shipped at 4 ℃ . Upon receipt, store it immediately at the temperature recommended below. |
| STABILITY & STORAGE |
Aliquot the reconstituted solution to minimize freeze-thaw cycles. Lyophilized protein should be stored at -20℃ to -80℃, stable for one year after receipt. Aliquots of reconstituted samples are stable at ≤ -20℃ for 3 months. |
| RECONSTITUTION |
Centrifuge tubes before opening. Dissolve the lyophilized protein in distilled water. Do not mix by vortex. It is recommended to dissolve the product at a concentration of twice the specified specification. |
| BACKGROUND |
Interleukin-1 beta (IL-1 beta) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta is synthesized in response to inflammatory stimuli as a 31 kDa inactive pro-form that accumulates in the cytosol. Cleavage of pro-IL-1 beta into the active 17 kDa protein requires the activation of inflammasomes, which are multi-protein complexes that respond to pathogens, stress conditions, and other danger signals. IL-1 beta play an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses to infection and injury. |
Specifications
| FORMULATION |
Lyophilized from sterile PBS, pH 7.4, 5% trehalose. |
|---|---|
| PURITY |
≥95% as determined by SDS-PAGE |
| ENDOTOXIN |
<1EU/ug |
| BIO ACTIVITY |
Immobilized Anti-Mouse IL-1B Antibody at 0.2 ug/mL (50 uL/well) can bind Mouse IL-1B with a linear range of 48.83 - 25,000 pg/mL. |
Data
Greater than 95% as determined by reducing SDS-PAGE.
Immobilized Anti-Mouse IL-1B Antibody at 0.2 ug/mL (50 uL/well) can bind Mouse IL-1B with a linear range of 48.83 - 25,000 pg/mL. (EC50 = 1.17 ng/mL)
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