SW837细胞

SW837细胞SW837细胞SW837人直肠腺癌细胞

Cell line name SW837

Synonyms SW-837; SW 837

Accession CVCL_1729

Resource Identification Initiative To cite this cell line use: SW837 (RRID:CVCL_1729)

Comments Part of: AstraZeneca Colorectal cell line (AZCL) panel.

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: FGFR genetic alteration cell panel (ATCC TCP-1034).

Part of: MD Anderson Cell Lines Project.

Part of: NCI RAS program mutant KRAS cell line panel.

Part of: TCGA-110-CL cell line panel.

From: Scott and White Clinic; Temple; USA.

Population: Caucasian.

Doubling time: 169 hours (Note=At 5th passage) (PubMed=1000501); 40.60 hours (PubMed=25944804).

Microsatellite instability: Stable (MSS) (PubMed=24755471; PubMed=25926053; PubMed=28683746; Sanger).

Omics: CNV analysis.

Omics: CRISPR phenotypic screen.

Omics: Deep exome analysis.

Omics: Deep proteome analysis.

Omics: Deep quantitative phosphoproteome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: miRNA expression profiling.

Omics: N-glycan profiling.

Omics: O-glycan profiling.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Omics: Transcriptome analysis by serial analysis of gene expression (SAGE).

Derived from site: In situ; Rectum; UBERON=

PubMed=1000501

Leibovitz A., Stinson J.C., McCombs W.B. 3rd, McCoy C.E., Mazur K.C., Mabry N.D.

Classification of human colorectal adenocarcinoma cell lines.

Cancer Res. 36:4562-4569(1976)

 

PubMed=924690; DOI=10.1002/ijc.2910200505

Kerbel R.S., Pross H.F., Leibovitz A.

Analysis of established human carcinoma cell lines for lymphoreticular-associated membrane receptors.

Int. J. Cancer 20:673-679(1977)

 

PubMed=286328; DOI=10.1073/pnas.76.3.1438; PMCID=PMC383267

Herlyn M., Steplewski Z., Herlyn D., Koprowski H.

Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies.

Proc. Natl. Acad. Sci. U.S.A. 76:1438-1442(1979)

 

PubMed=7104989; DOI=10.1016/0165-4608(82)90076-0

Chen T.-R., Hay R.J., Macy M.L.

Karyotype consistency in human colorectal carcinoma cell lines established in vitro.

Cancer Genet. Cytogenet. 6:93-117(1982)

 

PubMed=6652615; DOI=10.1016/0165-4608(83)90092-4

Chen T.-R., Hay R.J., Macy M.L.

Intercellular karyotypic similarity in near-diploid cell lines of human tumor origins.

Cancer Genet. Cytogenet. 10:351-362(1983)

 

PubMed=8464898; DOI=10.1073/pnas.90.7.2842; PMCID=PMC46192

Browning M.J., Krausa P., Rowan A.J., Bicknell D.C., Bodmer J.G., Bodmer W.F.

Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines.

Proc. Natl. Acad. Sci. U.S.A. 90:2842-2845(1993)

 

PubMed=7651727

Kastrinakis W.V., Ramchurren N., Rieger K.M., Hess D.T., Loda M., Steele G., Summerhayes I.C.

Increased incidence of p53 mutations is associated with hepatic metastasis in colorectal neoplastic progression.

Oncogene 11:647-652(1995)

 

PubMed=7824277

Eshleman J.R., Lang E.Z., Bowerfind G.K., Parsons R., Vogelstein B., Willson J.K.V., Veigl M.L., Sedwick W.D., Markowitz S.D.

Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer.

Oncogene 10:33-37(1995)

 

PubMed=9715273; DOI=10.1038/sj.onc.1201986

Eshleman J.R., Casey G., Kochera M.E., Sedwick W.D., Swinler S.E., Veigl M.L., Willson J.K.V., Schwartz S., Markowitz S.D.

Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53.

Oncogene 17:719-725(1998)

 

PubMed=10612807; DOI=10.1002/(SICI)1098-2264(200002)27:2<183::AID-GCC10>3.0.CO;2-P; PMCID=PMC4721570

Ghadimi B.M., Sackett D.L., Difilippantonio M.J., Schrock E., Neumann T., Jauho A., Auer G., Ried T.

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations.

Genes Chromosomes Cancer 27:183-190(2000)

 

PubMed=10737795; DOI=10.1073/pnas.97.7.3352; PMCID=PMC16243

Rowan A.J., Lamlum H., Ilyas M., Wheeler J., Straub J., Papadopoulou A., Bicknell D.C., Bodmer W.F., Tomlinson I.P.M.

APC mutations in sporadic colorectal tumors: a mutational 'hotspot' and interdependence of the 'two hits'.

Proc. Natl. Acad. Sci. U.S.A. 97:3352-3357(2000)

 

PubMed=11226274; DOI=10.1073/pnas.041603298; PMCID=PMC30173

Abdel-Rahman W.M., Katsura K., Rens W., Gorman P.A., Sheer D., Bicknell D.C., Bodmer W.F., Arends M.J., Wyllie A.H., Edwards P.A.W.

Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement.

Proc. Natl. Acad. Sci. U.S.A. 98:2538-2543(2001)