FTC-133细胞

FTC-133/FTC-133细胞系/FTC-133细胞株/FTC-133人甲状腺癌细胞

Cell line name FTC-133

Synonyms FTC133

Accession CVCL_1219

Resource Identification Initiative To cite this cell line use: FTC-133 (RRID:CVCL_1219)

Comments Group: Space-flown cell line (cellonaut).

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: TCGA-110-CL cell line panel.

Population: Caucasian.

Characteristics: Has a near-homozygous genome (NHG) (PubMed=29066502).

Microsatellite instability: Stable (MSS) (Sanger).

Omics: Deep exome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: Mitochondrial genome sequenced.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Anecdotal: Have been flown in space on Shenzhou-8 and on the ISS to study growth in microgravity (PubMed=23866977; PubMed=24196587; PubMed=25930030).

Misspelling: FTC-113; Cosmic=1889011.

Misspelling: CFT-133; PubMed=1384245; Note=In the French and Spanish abstracts where the abbreviation 'FTC' was translated to 'CFT' and thus also the cell line names.

Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.

PubMed=18713817; DOI=10.1210/jc.2008-1102; PMCID=PMC2582569

Schweppe R.E., Klopper J.P., Korch C.T., Pugazhenthi U., Benezra M., Knauf J.A., Fagin J.A., Marlow L.A., Copland J.A. 3rd, Smallridge R.C., Haugen B.R.

Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification.

J. Clin. Endocrinol. Metab. 93:4331-4341(2008)

 

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113

Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.

Signatures of mutation and selection in the cancer genome.

Nature 463:893-898(2010)

 

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662

Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.

Cancer Res. 70:2158-2164(2010)

 

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027

Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Nature 483:603-607(2012)

 

PubMed=23162534; DOI=10.3389/fendo.2012.00133; PMCID=PMC3499787

Saiselet M., Floor S., Tarabichi M., Dom G., Hebrant A., van Staveren W.C.G., Maenhaut C.

Thyroid cancer cell lines: an overview.

Front. Endocrinol. 3:133.1-133.9(2012)

 

PubMed=23833040; DOI=10.1210/jc.2013-2383; PMCID=PMC3763971

Landa I., Ganly I., Chan T.A., Mitsutake N., Matsuse M., Ibrahimpasic T., Ghossein R.A., Fagin J.A.

Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease.

J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013)

 

PubMed=23866977; DOI=10.1016/j.biomaterials.2013.06.054

Pietsch J., Ma X., Wehland M., Aleshcheva G., Schwarzwalder A., Segerer J., Birlem M., Horn A., Bauer J., Infanger M., Grimm D.

Spheroid formation of human thyroid cancer cells in an automated culturing system during the Shenzhou-8 Space mission.

Biomaterials 34:7694-7705(2013)

 

PubMed=24196587; DOI=10.1096/fj.13-243287

Ma X., Pietsch J., Wehland M., Schulz H., Saar K., Hubner N., Bauer J., Braun M., Schwarzwalder A., Segerer J., Birlem M., Horn A., Hemmersbach R., Wasser K., Grosse J., Infanger M., Grimm D.

Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space.

FASEB J. 28:813-835(2014)